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Interactions

A. Top Drug-Drug Interactions:

1.Nitrates (e.g., nitroglycerin, isosorbide dinitrate): Cialis and nitrates both lower blood pressure. Taking them together can cause a significant and potentially life-threatening drop in blood pressure (hypotension), leading to dizziness, fainting, or even heart attack or stroke. It is contraindicated to use Cialis with nitrates or recreational "poppers" (amyl nitrites).

2.Alpha-blockers (e.g., prazosin, terazosin, tamsulosin): Both Cialis and alpha-blockers relax blood vessels, which can lead to excessive blood pressure reduction when used together. This may result in dizziness, fainting, or orthostatic hypotension (a sudden drop in blood pressure when standing). If needed, your doctor may adjust the dosage or recommend spacing the medications.

3.Other antihypertensive drugs (e.g., atenolol, propranolol, enalapril, lisinopril): Cialis can enhance the blood-pressure-lowering effects of these medications. While this interaction is usually less severe than with nitrates or alpha-blockers, it can still cause dizziness or fainting in sensitive individuals. Close monitoring of blood pressure is recommended.

Other Drug-Drug interactions:

  • Ketoconazole, itraconazole (used to manage fungal infection)
  • Protease inhibitors (used to manage HIV infection) Ex. ritonavir, lopinavir
  • Phenobarbital, phenytoin, carbamazepine (medicines used for fits)
  • Rifampicin, erythromycin, clarithromycin (medicines used for bacterial infections)
  • Other medicines used to improve blood flow to the penis (Ex. sildenafil)

B. Drug-Food Interactions:

Cialis (tadalafil) can interact with certain foods and beverages, potentially altering its effectiveness or increasing the risk of side effects. Here are the key drug-food interactions to be aware of:

  1. Grapefruit and Grapefruit Juice: Grapefruit can increase the levels of tadalafil in your blood by interfering with its metabolism. This may amplify side effects, such as headaches, dizziness, or low blood pressure. Avoid consuming grapefruit or grapefruit juice while taking Cialis.
  2. Alcohol: Drinking alcohol with Cialis can enhance the blood pressure-lowering effects of the medication, leading to symptoms like dizziness, lightheadedness, or fainting. Limiting alcohol intake is recommended while using Cialis.
  3. High-Fat Meals: While Cialis can be taken with or without food, consuming it with a high-fat meal may delay its onset of action. Opt for lighter meals if rapid effectiveness is needed.
  4. Caffeine: Though not a direct interaction, combining Cialis with high caffeine intake might worsen side effects like headaches or increase heart rate in sensitive individuals.
A number of other people using this medication may have taken Cialis with other medications or high-fat foods.istsag-compare-pill-eria

C.

Here are the key drug-food interactions:

  1. : Though not a direct interaction, combining Cialis with high alcohol consumption may aggravate side effects, such as headaches or increase heart rate in sensitive individuals.
  2. : While you may take Cialis with a high-fat meal, you may miss your meal as it may affect its onset of action.
  3. : Though not a direct interaction, combining Cialis with high caffeine supply might worsen side effects, such as headaches or increase heart rate in sensitive individuals.

5.Nitrates (e.g.

Cialis has been shown to cause some mild side effects. Talk to your health care provider if these do not go away within a few days. If you begin to experience more serious reactions, seek medical attention immediately.

Common side effects reported from Cialis use include:

  • Headache
  • Indigestion
  • Heartburn
  • Upset stomach
  • Gas
  • Nausea
  • Flushing

More severe side effects include:

  • Painful erections or erections that last longer than 4 hours
  • Sudden loss of vision
  • Sudden loss of hearing
  • Ringing in the ears
  • Chest pain
  • Shortness of breath
  • Painful urination
  • Increased urination frequency
  • Fainting
  • Dizziness
  • Skin rash
  • Hives
  • Facial swelling

If you experience any of these side effects, seek medical attention immediately. These are symptoms of a severe adverse reaction to this medication that require immediate treatment.

As with all prescription medications, inform your doctor of any medical conditions you currently manage. Tell them about any and all medications, prescription drugs, and supplements you are taking before starting treatment with Cialis. Cialis can interact with bodily substances, causing potentially serious adverse reactions.

Specifically, you should inform your health care provider of any alpha-blocker, antifungal, HIV protease inhibitor, or high blood pressure medication you are taking. Remember to mention any herbal products you use, especially St. John’s wort.

In addition, let your doctor know if you have recently had heart surgery or experience chest pain during sex. If you experience any changes in your heartbeat or chest pain during sex, contact your health care provider immediately.

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This medication can cause potential side effects and cost. If you experience any of these, you should contact your doctor immediately:

  • Severe skin effects
  • Sudden vision loss
  • Sudden hearing decrease
  • Sudden blood pressure decrease
  • Sudden erection pain
  • Sudden loss of body hair

As with all prescription medications, inform your doctor if you experience any changes in your. This includes any dizziness caused by your high or low blood pressure,mega-3 thyroid medicine, calcium-channel blockers, or sugars. Listed when taking sugars and foods into account.

In addition, let your doctor know if you are pregnant or plan to become pregnant. If you are, see your doctor regularly.

In addition, if you have ever had an allergic reaction to Cialis or any other medication before, you should contact a doctor immediately:

  • Allergy tests may be needed
  • Diagnostic tests such as blood test or imaging tests may be needed
  • Assay for prostate specific antigen (PSA) tests
  • Eiciency tests or prostate specific antigen (PSA) tests
  • Erectile dysfunction tests
  • Erectile dysfunction tests should not be used in combination with any of the above.

In addition, let your doctor know if you are breastfeeding. Cialis can affect the developing fetus and could affect the mother’s birth control. If you are a NYU Grossman Grossman Grossman Grossman at any time, see your doctor immediately.

Last updated 4 June 2024

Tests in men with ED:

Repeat doses of tadalafil for up to 2 weeks before sexual activity.

See resultsif ED continues despite treatment.

Tadalafil is an erectile dysfunction (ED) medication primarily used to treat erectile dysfunction (ED) in men. It works by increasing blood flow to the penis, aiding in achieving and maintaining an erection. It is important to note that tadalafil does not work on the sexualITCHS stage – men can still take it for ED if they are under 18 years old. Men with ED should consult a healthcare professional for a suitable treatment plan, including the use of tadalafil.

ED treatments available

Tadalafil works by increasing blood flow to the penis, helping to achieve and sustain an erection. It is available as an oral tablet and a topical cream, available under the brand name Cialis. Tadalafil tabletsare also available, both as oral and topical formulations, and as an injection. Both treatments contain the same active ingredient, tadalafil, and work in the same way to achieve and maintain an erection. However, some men may find that their tadalafil injection does not work as well as the oral medication for this condition. The medication is also sometimes available through local pharmacy such as Dr Fox. It is important to consult with a healthcare professional before starting any ED treatment.

What are the benefits of tadalafil for ED?

Tadalafil for ED is typically used in the following three ways to achieve and maintain an erection:

1. Oral administration

  • Tadalafil is typically taken as a single oral tablet, taken as needed, approximately one hour before sexual activity. This allows for a rapid onset of action.
  • Tadalafil is also usually taken as a once-daily, once-daily, once-daily (‘on demand’) treatment.

2. Topical cream

  • Topical cream, available under the brand name Cialis, is applied directly to the skin. This cream contains the same ingredients as tadalafil and works in the same way.
  • Topical cream is often recommended for men who have difficulty or prefer to use an ED cream, as it can be applied topically.
  • Topical cream may be effective for men who are sensitive to the side effects of tadalafil.

3. Intra-arterial injections

  • Injections are typically given into the penis, usually once or twice daily, to achieve and maintain an erection. The injections are typically indicated in men who are sensitive to the injection, such as men who have difficulty or prefer to use an ED cream, or men who are unable to achieve or maintain an erection due to conditions other than erectile dysfunction.

The advantages of using tadalafil for ED are:

  • Enhanced sexual confidence and performance
  • Improved sexual satisfaction and confidence
  • Increased confidence in sexual relationships and performance
  • Better control over ejaculation and ejaculation timing

Tadalafil vs Sildenafil: What’s the Difference?

Both tadalafil and sildenafil are phosphodiesterase type 5 (PDE5) inhibitors, specifically found in the body. Tadalafil is found in both men’s and women’s blood vessels, with an estimated prevalence of about 30% in men with ED. Sildenafil is also found in men’s blood vessels, but with a prevalence of less than 30%. Tadalafil is generally well-tolerated, with few reported side effects. However, tadalafil has a higher risk of side effects than sildenafil, and is generally not recommended for women. Tadalafil is a PDE5 inhibitor, with an estimated prevalence of about 10% in women and 5% in men.

Both tadalafil and sildenafil have been found to be effective in treating ED in some men. The majority of men with ED do so with the aid of medications like Viagra (sildenafil citrate), Cialis (tadalafil), and Levitra (vardenafil).

Cialis has been shown to cause some mild side effects. Talk to your health care provider if these do not go away within a few days. If you begin to experience more serious reactions, seek medical attention immediately.

Common side effects reported from Cialis use include:

  • Headache
  • Indigestion
  • Heartburn
  • Upset stomach
  • Gas
  • Nausea
  • Flushing

More severe side effects include:

  • Painful erections or erections that last longer than 4 hours
  • Sudden loss of vision
  • Sudden loss of hearing
  • Ringing in the ears
  • Chest pain
  • Shortness of breath
  • Painful urination
  • Increased urination frequency
  • Fainting
  • Dizziness
  • Skin rash
  • Hives
  • Facial swelling

If you experience any of these side effects, seek medical attention immediately. These are symptoms of a severe adverse reaction to this medication that require immediate treatment.

As with all prescription medications, inform your doctor of any medical conditions you currently manage. Tell them about any and all medications, prescription drugs, and supplements you are taking before starting treatment with Cialis. Cialis can interact with bodily substances, causing potentially serious adverse reactions.

Specifically, you should inform your health care provider of any alpha-blocker, antifungal, HIV protease inhibitor, or high blood pressure medication you are taking. Remember to mention any herbal products you use, especially St. John’s wort.

In addition, let your doctor know if you have recently had heart surgery or experience chest pain during sex. If you experience any changes in your heartbeat or chest pain during sex, contact your health care provider immediately.

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Cialis_Warnings

Cialis can cause potentially serious side effects, including:

As with all prescription medications, inform your doctor if you are taking any of the following:

  • Alcohol
  • High blood pressure
  • Pregnancy
  • Erectile dysfunction
  • Liver disease
  • Stomach problems
  • Stomach pain
  • Stiff or tender breasts

These may not be immediately accessible. If you experience symptoms such as rash, dizziness, fainting, prolonged erection, or sudden numbness or tingling, seek medical attention immediately.

Cialis can cause potentially serious allergic reactions. If any new or additional reactions occur, contact your health care provider immediately.